2015 FALL - Opportunities in Translational Science Biopharma R&D including Information Management, Analysis and Visualization

DATE, LOCATION & HOST

The 2015 fall PRISME Forum Technical Meeting was held Thursday, the 19th of November, 2015 and was hosted by Bristol-Myers Squibb at its Plainsboro Campus located at 777 Scudders Mill Road, Plainsboro Township, NJ 08536.

The meeting was preceded by a networking reception the evening of Wednesday, the 18th of November.

PRISME Forum Technical Meeting Chair:
Martin Leach, Alexion

PRISME Forum Chair:
Olivier Gien, Sanofi

FALL 2015 TECH MEETING

 

Thursday, May 21, 2015

 

 

Meeting hosted by Bristol-Myers Squibb

 

Opportunities for Translational Science in Biopharma R&D Including Information Management, Analysis and Visualisation

Translational Science is a discipline often described as the rapid iteration of learnings from bench to bedside. Those learnings encompass activities such as disease understanding, target identification and credentialing, biomarker research and patient stratification. Translational Science is seen as one of the key levers in pharma’s search for this R&D productivity goal and self-evidently, Translational Science Information Management, Analysis and Visualisation is a key supporting discipline. This PRISME Forum Technical Meeting will set out the current situation in TS Information Management, Analysis and Visualisation and then explore where improvements are needed and how these improvements might be effected. Furthermore, priorities will be assigned to these improvements bearing in mind scientific need and technical feasibility. Additionally, the meeting will review how the PRISME Forum might stimulate new project ideas within this domain for an IMI-2 or indeed other consortium-based initiatives. A PRISME Forum Technical Meeting Advisory Committee (TMAC) has been set up to provide guidance on agenda topics and appropriately qualified speakers. The committee members are listed below:

Anastasia Christianson BMS Head of Translational R&D IT
Jasmin Saric Boehringer-Ingelheim Head of IT Translational Science & Epidemiology
John Wise PRISME Forum Programme Coordinator
Lars Greiffenberg Abbvie Director – R&D IT and Translational Informatics
Martin Leach Alexion VP, R&D IT
Sandor Szalma Janssen Head, Translational Informatics & External Innovation

The PRISME Forum Technical Meeting Advisory Committee will be looking for qualified speakers to address relevant topics including:

  • Use cases demonstrating how TS and its associated technologies have enhanced bio-pharma R&D
  • New TS technologies – empowering new insights and services – thereby lowering the barrier to entry to bio-pharma R&D
  • Future directions for TS including the exploitation of “big data”
  • The integration of TS data across multiple platforms including traditional enterprise systems
  • Experiences and examples from suppliers of TS technologies that either directly – or by analogy – will provide opportunities for R&D and R&D IT.
  • The need for better access to better ontology for better description of translational science phenomena

PRISME Forum members will:

  • Enhance their understanding of translational science and the opportunities for R&D IT to support and develop that discipline
  • Take back to their parent organizations tactical learnings that can be deployed quickly to support translational science and,
  • As a stretch goal identify a common, pre-competitive obstacles that can best be palliated or cured by a cross-company, inter-disciplinary project team working under that umbrella of a grant awarding organization such as the IMI.

For more information or for any suggestions, please get in touch with John Wise, Programme Coordinator for the PRISME Forum on jcmwise@prismeforum.org or +44 7768 173518.

All sessions will be held at Bristol-Myers Squibb’s campus in Plainsboro, NJ, USA.

TIME

SESSION

SPEAKER/CHAIR

Wednesday, Nov 18, 2015

18:45Gather in hotel lobby for departure to PRISME Forum (Business + Technical) Group Reception

Thursday, Nov 19, 2015

8:00Shuttle transfer between hotel and meeting venue
8:30Check-in; poster installation
8:45Welcome NotesOlivier Gien, Chair, PRISME Forum; Global Head, Clinical IT, Sanofi
8:50 IntroductionMartin Leach, Technical Meeting Chair, PRISME Forum; VP, R&D IT, Alexion
9:00

SESSION 1: PERSPECTIVES

Martin Leach, Technical Meeting Chair, PRISME Forum; VP, R&D IT, Alexion
9:00L1
Translational Science: the Importance in Biopharma R&D
Mike Burgess, Head of Exploratory Clinical and Translational
Research, Bristol-Myers Squibb
9:30L2
Converting Available Data into Useful Information in the Omics Era
George Davey-Smith, Professor, University of Bristol
10:00L3
Big Data and Translational Research at Google-Scale
Vik Bajaj, Chief Scientist, Google Life Sciences
10:30Coffee Break
11:00

SESSION 2: LIGHTNING TALKS

Martin Leach, Technical Meeting Chair, PRISME Forum; VP, R&D IT, Alexion
11:00LT1
Genotype-Phenotype Data Driving Medical Discovery and Patient Management
Joe Donahue, Senior Vice President, BioReference Laboratories
11:10LT2
Stratifying Tumor Genomic Alteration Landscapes Through Comprehensive Analytics
Eric Neumann, Vice President of Knowledge Informatics, Foundation Medicine
11:20LT3
Using Machine Learning and Expert Human Guidance to Automate Clinical Data Integration to CDISC Standards
Timothy Danford, Software Engineer, Tamr, Inc.
11:30MODERATED PANEL DISCUSSION - Q&A
12:00

SESSION 3a: POSTERS (Intro)

CHAIR: Lars Greiffenberg, Director, R&D IT and Translational Informatics, Abbvie
12:05Poster Session (Three 15 minute rotations)
P1
Power of Reverse Engineering and Forward Simulation Platform for Driving Precision Medicine
Iya Khalil, ‎Executive Vice President and Co-Founder, GNS Healthcare
P2
Data Integration Challenges and Opportunities in Translational R&D
Albert Wang, Associate Director, Exploratory Clinical & Translational Research IT, Bristol-Myers Squibb
P3
Translational Science: Current Information Challenges and Solutions
Phil Scordis, ‎Director, Translational Bioinformatics, UCB
P4
Harness Patient Preference from Social Media
Mark Wolff, Consultant, SAS Institute
P5
Translational R&D Analytics: Powering Data-Driven Advances in Immunotherapy
Kaushal Desai, Associate Director, Translational R&D Analytics and Decision-Support, Bristol-Myers Squibb
P6
TranSMART & eTRIKS – Current Status
Jay Bergeron, Director, Translational and Bioinformatics, Pfizer
12:50

Lunch

13:30

SESSION 3b: POSTERS

CHAIR: Lars Greiffenberg, Director, R&D IT and Translational Informatics, Abbvie
Poster Session (Remaining three 15 min rotations)
14:15

SESSION 4: PLENARY PRESENTATIONS

CHAIR: Anastasia Christianson, Head of Translational R&D IT, Bristol-Myers Squibb
14:15L4
Linked Data at Work in Translational Science
Hans Constandt, CEO and Co-Founder, ontoforce
15:15Coffee Break

Preparations for SESSION VI: BRINGING IT ALL TOGETHER

Table Captains: Sandor Szalma, Jasmin Saric, Jay Bergeron and Lars Greiffenberg will meet to frame the structure of the session. A slide to provide clear instructions for the round-table discussion groups will be created.
15:45

SESSION 5: KEYNOTE PRESENTATION

CHAIR: Jasmin Saric, Head of IT Translational Science & EpidemiologyBoehringer-Ingelheim
15:45Keynote Lecture
A Different Industry Perspective on Multiple Input Data Analytics
Tara Grabowsky, Chief Medical Officer, Vencore
Oodaye Shukla, Chief Data Scientist, Vencore
16:15

SESSION 6: BRINGING IT ALL TOGETHER

CHAIR: Sandor Szalma, Head, Translational Informatics & External Innovation, Janssen Research & Development LLC
16:15Objective
Create a preliminary draft of a topic proposal for review by the IMI DKM SGG or another relevant project organising body.

Breakouts
The audience will be divided in four groups. The table captains listed above will coordinate the groups’ review, consideration and drafting advice for the next steps (on the basis of the day’s proceedings and the instructions displayed on the big screen).
17:00Plenary: Table Captains' Feedback
17:15Plenary: Discussion of readout; Determine next steps
17:30AwardsMartin Leach, Technical Meeting Chair, PRISME Forum; VP, R&D IT, Alexion
17:45Networking Reception
19:30Return to Hotel

 

PRISME Forum’s Tech Meeting App is available at https://my.yapp.us/PRISMETECH.

HOTEL
The hotel for this meeting is The Westin Princeton at Forrestal Village located at:

201 Village Boulevard
Princeton, NJ 08540
United States

The discounted rate, for single and double rooms, inclusive of breakfast has ended.

To reserve a room, please call the hotel at +1 (609) 452-7900 or book online: http://www.westinprinceton.com/

DISTANCE BETWEEN MEETING VENUE AND LOCAL AIRPORTS
Newark International Airport (Code EWR) 41 mi
Philadelphia International Airport (Code PHL) 54 mi
JFK International Airport (JFK) is 65 mi
La Guardia International Airport (LGA) is 69 mi
CAR SERVICES

UBER*:

*THIS PROMOTION IS FOR FIRST TIME UBER USERS ONLY

Receive up to $25 off on your fare when you sign up with Uber using the following link (promotion code “PRISME”)

Click here to sign up for Uber and claim $25 off*

Joe’s Princeton Taxi & Car Services:

$110 from Newark

$235 from JFK

$125 from Philly

Joe’s Princeton Taxi Website

(609) 436-0707

DSM Taxi*:

$115 from Newark (cash) / $125 (credit card)

$225 from JFK  (cash) / $245 (credit card)

$125 from Philadelphia (cash) / $135 (credit card)

DSM Taxi Service

(609) 722-1913

*10% discount is available if you inform the dispatcher you are part of the PRISME Forum (please remind the dispatcher a 10% discount has been agreed upon)

TRAIN STATION
The closest train station to the meeting venue is Princeton Junction located on Wallace Road, Princeton Junction, NJ 08550

For tickets and timetables visit:
http://www.njtransit.com/

MEETING AND SOCIAL EVENT VENUE TRANSFERS
Morning and afternoon transfers will be offered between the hotel, the meeting venue and the social/networking events (per program outline).